磁性MnFe_2O_4/Ag复合纳米粒子的制备与抑菌性能测试

The Preparation and Antibacterial Property Testing of Magnetic MnFe_2O_4/Ag Composite Nanoparticles

采用水热法合成了磁性空心MnFe2O4纳米粒子,然后用3-氨丙基三乙氧基硅烷对其表面进行了改性并吸附银离子,还原后成功制备了磁性MnFe2O4/Ag复合纳米粒子,并采用X射线衍射仪、透射电镜、磁强计、紫外光谱等对试样进行了表征。通过抑菌圈法对MnFe2O4/Ag复合纳米粒子的抑菌性能进行了测试。结果表明:磁性空心MnFe2O4纳米粒子没有抑菌性能;MnFe2O4/Ag对大肠杆菌的抑菌圈半径为1.78 cm,对金黄色葡萄球菌的抑菌圈半径为2.14 cm;MnFe2O4/Ag的抑菌持久性检测结果说明,所制备的载银磁性复合纳米粒子抑菌剂的稳定性较好,抑菌性能较持久。

Magnetic hollow MnFe2O4 nanoparticles were prepared by hydrothermal method and the nanoparticles surface were modified by（3-aminopropyl） triethoxysilane（APTES）, then absorbed silver ions. After reduction the magnetic MnFe2O4/Ag composite nanoparticles were successfully prepared. The X-ray diffraction, transmission electron microscopy, magnetometer and ultraviolet spectrometer were applied to characterize the samples. Inhibition zone method was used to detect the antimicrobial effect of MnFe2O4/Ag composite particles. The characterization and detection results showed that the parent hollow magnetic MnFe2O4 was not active in antimicrobial property, and the inhibition zone radius of the composite MnFe2O4/Ag to E.coli was 1.78 cm and that to S. aureus was 2.14 cm. The MnFe2O4/Ag antibacterial durability test results showed that Ag-carrying magnetic composite particles had high stable and lasting antibacterial performance.