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维生素E琥珀酸酯抑制人胃癌细胞生长的研究 被引量:21

Inhibition of human gastric carcinoma cell growth by vitamin E succinate
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摘要 采用体外细胞培养的方法 ,观察维生素 E琥珀酸酯 (VES)对人胃癌细胞 (SGC- 790 1)生长的影响 ,并利用 MTT法比较 VES和α-生育酚对胃癌细胞生长的作用效果。结果表明 :VES(5、10和 2 0μg/ m l)对胃癌细胞生长有明显抑制作用 ,而 α-生育酚在同样剂量对肿瘤细胞生长无抑制作用。这提示 VES具有不同于维生素 E的抗癌机理。 The effects of vitamin E succinate(VES) on the growth of human gastric carcinoma cell (SGC 7901) were examined and compared with the effects of α tocopherol by MTT assay. It was found that VES(5,10 and 20 μg/ml)inhibited cell growth significantly, but α tocopherol did not show any inhibition effects. The results showed that the anticancer effect of VES and the anticancer mechanism of VES is different from α tocopherol.
出处 《卫生研究》 CAS CSCD 北大核心 2000年第3期172-174,共3页 Journal of Hygiene Research
基金 国家自然科学基金!资助项目 ( No.3 9870 662 )
关键词 维生素E琥珀酸酯 胃癌 细胞生长 抑制作用 vitamin E succinate, human gastric carcinoma cell (SGC 7901), α tocopherol
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