辅助治疗与新辅助治疗在胰腺癌治疗中的作用

Role of neoadjuvant therapy and adjuvant therapy in treatment of pancreatic cancer

胰腺癌是一种高度恶性的肿瘤.在西方国家中,胰腺癌是恶性肿瘤中的第4位死亡原因,而且胰腺癌的手术切除率低.所以胰腺癌的综合治疗显得尤为重要.胰腺癌的术前的新辅助治疗与术后的辅助治疗是治疗胰腺癌的重要组成部分.通过胰腺癌的辅助治疗,可以提高胰腺癌患者的生存时间与生活质量.而胰腺癌的新辅助治疗则可以降低胰腺癌临床病期缩小原发病灶及转移的淋巴结,为无手术条件的患者提供手术的可能,提高根治性手术的切除率.减少术中出血和术后并发症.提高患者的术后生存率与生活质量.本文简要介绍了胰腺癌辅助治疗与新辅助治疗的方法.

Pancreatic cancer is a highly malignant tumor that has a low resection rate. In Western countries, pan- creatic cancer is the fourth cause of death in ma- lignant tumors. Combined therapy is particularly important for the treatment of pancreatic cancer. Preoperative neoadjuvant therapy and postopera- tive adjuvant therapy are important parts of com- bined treatment for pancreatic cancer. Adjuvant therapy can improve survival and quality of life of patients with pancreatic cancer, and neoadjuvant therapy can reduce the primary lesion and lymph node metastasis, provide patients with the pos- sibility of surgery to improve radical resection, de- crease intraoperative bleeding and postoperative complications, and improve postoperative survival and life quality of patients. This article reviews the role of adjuvant therapy and neoadjuvant therapy in the management of pancreatic cancer.