蜂胶的药理作用研究

Study on the Pharmacologic Effect of Propolis

蜂胶药理作用的研究结果显示:对小鼠有抗疲劳耐缺氧作用,能阻止高脂血症模型大鼠血粘度和血脂(Th、TG、LDL-C)升高(P<0.05～0.01),但红血球比积(Hct)和高密度脂蛋白胆固醇(HDL-C)改变不显著;能增强免疫抑制模型小鼠腹腔巨噬细胞吞噬功能(P<0.05),增加胸腺指数(P<0.05),但脾指数改变不明显。给小鼠灌服蜂胶LD_(50)>7500 mg/kg。

Pharmacologic effects of propolis were investigated in this article.The results suggested that propolis has pharma-cologic functions in many aspects.It is a new-type medicine derived from animal in pharmacology and food both.To small mouse, propolis showed the functions of anti-fatigue and endurance to lack of oxygen.To high-blood-lipid-model mouse, it prevented increase of blood-mucus and blood lipid(TC,TG,LDL-C) (P<0.05-0.01),but there were insignificant changes to red-blood-cell proportion (HCT) and high-density lipoprotein chelesteral (HDC-C) .To small immunosuppessive-model mouse, propolis could strengthen macrophagocyte phagocytosis in the abdominal-cavity (P<0.05),and increase the thymus-index (P < 0.05), but there were insignificant changes to the spleen-index.The LD50 > 7500 mg/kg to small mouse.