睾丸间质细胞瘤的临床分析

Clinical study of testicular Leydig cell tumor

目的:探讨睾丸间质细胞瘤的临床特点,提高睾丸间质细胞瘤的诊断和治疗水平。方法:报告1例睾丸间质细胞瘤患者的临床资料,结合相关文献进行分析。结果:术中快速冰冻病理结果为良性睾丸间质细胞瘤,行保留睾丸的肿瘤剜除术,术后随访4个月未见肿瘤复发及转移。结论:睾丸间质细胞瘤是临床较为少见的一种肿瘤,术前诊断较为困难,确诊仍依赖术后病理组织学检查。治疗主要以手术治疗,传统的手术方法采用根治性睾丸切除术,然而对于青春期前患者、双侧辜丸间质细胞瘤等患者,特别是病理检查确诊是良性睾丸间质细胞瘤患者,可以施行保留睾丸的肿瘤剜除术,行肿瘤剜除术前应常规行快速冰冻病理检查。

Objective：To discuss the clinical characters of the testicular Leydig cell tumor（LCT）,to improve diagnosis and treatment level.Methods：A case of Leydig cell tumor was analyzed,the related literature was reviewed.Results：The result of quick frozen section pathological analysis during the surgery was benign tumor,the patient underwent testis sparing surgery（TSS）.No local recurrence or distant metastasis was detected during 4 months follow-up.Conclusion：Leydig cell tumor was rare tumor,preoperative diagnosis was difficult,diagnosis mainly rely on pathological examination.Surgery was the main therapeutic method,the traditional surgery method was the radical orchiectomy.But for pre-adolescent patients with bilateral testicular Leydig cell tumor or single testis,especially their pathological grade was benign,TSS was a feasible and safe Choice.Quick frozen section pathological analysis is the prerequisite of TESS.