卵巢甲状腺肿15例临床病理分析

Clinical pathologic analysis of 15 cases of struma ovarii

目的 探讨卵巢甲状腺肿的临床及病理特点 ,提高对本病的认识。方法 对 15例卵巢甲状腺肿进行临床病理回顾性分析 ,并综合文献复习。结果 本病发病率在卵巢成熟畸胎瘤中占 3 .75 % ,临床表现为非特异型盆腔肿块 ,或无症状被体检发现。病理诊断必须具备以下四点之一。 ( 1)肿瘤完全由甲状腺组织构成 ;( 2 )肿瘤 5 0 %以上由甲状腺组织构成 ,其它为畸胎瘤成份 ;( 3 )肿瘤虽然未超过 5 0 % ,但伴有明显甲亢症状 ;( 4 )在成熟畸胎瘤的标本中 ,有肉眼可见的甲状腺组织。组织学分型 :单纯型、混合型、甲亢型、滤泡癌变型。结论 卵巢甲状腺肿是非常少见的肿瘤 ,多为良性 。

Objective To discuss clinical and pathologic features of the struma ovarii and improve our knowledge of the disease. Methods 15 cases of struma ovarii were analysed retrospectively and the literature was reviewed.Results The incidence of the struma ovarii was 3.75% in mature teratoma of ovary.The clinical features were non-specific pelvic tumor or no symptom found in the patients in physical examination.The pathologic-diagnosis of struma ovarii had to have one of the following items:(1)The tumor consisted completely of thyroid tissue;(2)The thyroid tissue made up over 50% of the tumor while the rest of the tumor was teratoma tissue.(3)The composition of thyroid tissue in the tumor was bellow 50%,but the patient had the symptom of thyroidism.(4)The thyroid tissue could be found with nakedeyes in the specimen of mature teratoma. Conclusions Struma ovarii is a kind of rare trmor and is mainly benign.It has unique morphological feature with a good prognosis.