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葡萄膜炎的生物治疗进展 被引量:3

Advance in the biological therapy of uveitis
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摘要 葡萄膜炎多发于青壮年,多为自身免疫性疾病,常反复发作。研究表明,生物制剂可以干扰机体内引起炎症反应过程的具有特定分子或途径,在葡萄膜炎的发病过程中发挥了关键的治疗作用,以达到治疗葡萄膜炎的目的。本文意在探讨抗肿瘤坏死因子制剂、白细胞介素受体拮抗剂、干扰素、抗淋巴细胞特异性抑制剂等生物制剂在葡萄膜炎治疗过程中的治疗进展。 Most of uveitis is a kind of autoimmune diseases. Uveitis often occurs in the young adults and frequently relapses. Studies show that biological preparations can interfere with the specific molecules or pathways which cause inflammatory reaction process in the body, which play a critical role in the treatment of onset progress of uveitis to achieve the purpose of treatment of uveitis. This paper discusses the progress of biological preparations such as anti tumor necrosis factor agents, interleukin receptor antagonists, interferon and anti lymphocyte specific inhibitors applied in the treatment of uveitis.
作者 李燕利 杨炜
出处 《国际眼科杂志》 CAS 2013年第6期1147-1151,共5页 International Eye Science
关键词 葡萄膜炎 生物制剂 抗肿瘤坏死因子 干扰素 uveitis biological preparation anti tumornecrosis factor interferon
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