摘要
目的分析垂体瘤质地的相关因素,为术前评估和手术方法提供依据。方法回顾性分析70例垂体瘤患者的临床资料,分析患者临床资料、影像学结果、手术资料等,分析术前评估垂体瘤质地的相关因素。结果瘤体质地软的患者平均胶原含量显著低于质地韧的瘤体(P<0.01)。而质地软的瘤体T2WI瘤体/白质信号显著高于质地韧的瘤体(Pt<0.01)。T2WI瘤体/白质信号比与瘤体胶原含量的相关性结果显示呈负相关(r=-0.873,P<0.05)。结论组织胶原蛋白含量是判断肿瘤质地的一个重要指标,而MRI中T2WI瘤体/白质信号比与组织胶原蛋白含量呈负相关,可以作为术前评估垂体瘤质地的一个指标。
Objective To analyze methods of preoperative assessment of the quality of pituitary adenoma. Methods Retrospective analyzed clinical data of 70 cases with pituitary adenoma. Clinical data,imaging results,operation data were analyzed. Correlation factors of preoperative assessment of the quality of pituitary adenoma were analyzed. Results Collagen volume fraction of soft texture was lower than hard texture(P 〈 0.01). T2WI tumor/white matter signal of soft texture was higher than hard texture(P 〈 0.01). T2WI tumor/white matter signal showed negative correlation with collagen volume fraetion(r=-0.873,P 〈 0.05). Conclusion Collagen volume fraction is an important index for preoperative assessment of the quality of pituitary adenoma. T2WI tumor/white matter signal shows negative correlation with collagen volume fraction.
出处
《中国医药科学》
2013年第10期49-50,共2页
China Medicine And Pharmacy
关键词
垂体瘤
手术
质地
Pituitary adenoma
Operation
Quality