羊膜囊预测早孕期妊娠结局的临床应用探究

Clinical application of amniotic sac prediction of pregnancy outcome in early pregnancy

目的探讨羊膜囊在预测早孕期妊娠结局的临床应用。方法选取我院及广东同江医院2012年7月～2013年2月进行阴道超声检查并选择继续妊娠的早孕妇女为研究对象。采用流行病学巢氏病例对照研究方法，以妊娠6～28周期间超声检查胚胎停育或自然流产的孕妇为异常妊娠组，以超声检查胚胎正常发育的孕妇为正常妊娠组，通过回顾性研究孕妇在6—10周期间超声检查羊膜囊、卵黄囊、妊娠囊、头臀长异常率的发生情况，来探讨羊膜囊、卵黄囊、妊娠囊、头臀长与胚胎发育的关系，从而评价羊膜囊在早孕妊娠结局中的预测作用。结果正常妊娠组孕囊大小符合停经史，孕囊完整，圆形或类圆形，羊膜囊平均直径接近于CRL，且卵黄囊的平均内径在3—8mm之间。异常妊娠组孕囊大小不符合停经史，孕囊变大、变小，不规则或锯齿状，卵黄囊异常，8周后未见胎心，难免流产，胚胎停止发育。结论羊膜囊的检测对于预测早孕期妊娠结局具有重要的临床价值。

Objective To investigate the clinical application of amniotic sac in predicting the pregnancy outcome of early pregnancy. Methods Patients in our hospital and Guangdong Tongjiang Hospital from June 2012 to March 2014 were examined by transvaginal ultrasonography and who choose to continue pregnancy pregnant as the object of study. The epidemiology of nested case-control study method would be used to study. The pregnancy with 6-28 weeks used with ultrasound examination embryo or spontaneous abortion of pregnant women as abnormal pregnancy group. The others with ultrasonography of normal embryonic development of pregnant women were as normal pregnancy group. We use the retrospective study to analyse pregnant women at 6-10 weeks occurred during ultrasound examination of the amniotic sac,yolk sac,the gestational sac,crown-rump length abnormal rate,to explore the amniotic sac,yolk sac,the gestational sac,crown-rump length and embryonic development,so as to evaluate the amniotic sac in early pregnancy outcome prediction in. Results With the history of menopause group,the gestational sac size of normal pregnancy,gestational sac full,round or oval,the amniotic sac diameter close to the CRL,and the average diameter of yolk sac in 3-8 ram. Abnormal pregnancy gestational sac size does not meet the menopause history,gestational sac larger,smaller,irregular or jagged,yolk sac abnormality,after 8 weeks,no fetal heart,inevitable abortion,embryonic development stops. Conclusion The detection of amniotic sac has important clinical value in predicting pregnancy outcome in early pregnancy.