妊娠期糖尿病患者C-反应蛋白和尿微量白蛋白测定的临床意义

Detection of C-reactive protein combined with urine microalbumin in patients with gestational diabetes mellitus and their clinical significance

目的探讨妊娠期糖尿病患者C-反应蛋白和尿微量白蛋白检测的临床价值。方法对38例GDM患者(GDM组)及30例健康孕妇(对照组)采血及晨尿检测CRP及UMA水平并进行比较。结果 GDM组的CRP及UMA水平均显著高于对照组,两组比较差异有统计学意义(P<0.01)。结论 CRP与UMA联合检测有助于GDM的早期诊断,对评价患者病情及指导治疗有重要价值。

Objective To investigate the clinical value of detecting C-reactive protein（CRP） combined with urine microalbumin（UMA）in patients with gestational diabetes mellitus（GDM）. Methods The levels of CRP and UMA in 38 patients with GDM（GDM group） and 30 healthy pregnant women（control group） were detected and compared. Results The levels of CRP and UMA in GDM group were significantly higher than the control group（P 〈 0.01）. Conclusion Detection of CRP combined with UMA in patients with GDM is helpful to early diagnosis, and have important clinical value for evaluating the severity and directing treatment.