影响诺氟沙星葡萄糖注射液质量因素的考察

Study of the influence factors to the quality of injectio norfloxacixi et glucosi

目的 :考核产生诺氟沙星葡萄糖注射液变黄绿色等质量变化的主要因素。方法 :从Fe3+ 的污染 ,活性炭的不同加入量等几个方面进行实验。结果 :Fe3+ 的污染是该注射液变黄绿色的主要原因 ,活性炭加入量增加对诺氟沙星的吸附量也呈线性增加。结论 :配制该注射液时应尽量减少与不锈钢容器的接触时间 ,以及注意控制活性炭的用量。

OBJECTIVE:To study the key factor that injection was yellowed.METHOD:The effect of Fe 3+ .Charcoal and others rspects were studied.RESULTS:Fe 3+ was the key facfor that yellowed the injection.CONCLUSION:The time of contacting with stainless steel container in preparation and the quantity of charcoal used should be controlled.