垂体瘤手术及其并发症的防治

Clinical analysis of pituitary tumor operation and complication prevention

目的分析经蝶入路治疗垂体瘤手术方法及并发症发生情况,提出并发症防治策略。方法 256例垂体瘤患者行经蝶入路手术切除肿瘤治疗,术后观察并发症发生情况,并与文献报道结果进行比较分析。结果 256例患者尿崩和脑脊液漏发生率明显低于文献报道(P<0.01);其他并发症包括水电解质紊乱、继发性出血、视力障碍加重、下丘脑功能紊乱、眼肌麻痹和死亡等,两组间比较差异无统计学意义(P>0.05)。结论垂体瘤手术后并发症较多,临床应强调手术操作方法、明确入路、适当填充,同时应有效防治并发症。

Objective To retrospectively analyze and record the operation method of transsphenoidal approach for the treatment of pituitary tumors and complications,and put forward the prevention and treatment of complications strategies according to the clinical experience.Methods 256 cases of pituitary tumor patients with transsphenoidal operation resection of the tumor treatment,postoperative complications, and with Chen Longyi in 2010 reported results of a comparative analysis.Results 256 cases of patients with diabetes insipidus and cerebrospinal fluid leakage incidence was significantly lower than Chen Long-yi＇s Group（P 0.01）;other complications include water and electrolyte disorders,secondary hemorrhage,visual impairment worsened,hypothalamic function disorder,ophthalmoplegia and death,the two groups had no significant difference（P 0.05）.Conclusions More complications of pituitary tumor after operation, clinical should emphasize the operation method of operation,a clear approach,fit,and doctors should improve their own responsibility,to summarize the clinical experience,effective prevention and treatment of complications.