摘要
运用电镜 ,对一次性电击引起大鼠脑内GrayⅠ型突触界面某些结构的变化进行了定量观察。在海马CA3区 ,突触后膜致密物质显著增厚 (P <0 0 5) ,突触间隙宽度极显著增宽 (P <0 0 1 ) ;在大脑皮层感觉运动区 ,突触界面曲率显著变大 (P <0 0 5)。突触界面弯曲类型无显著性差异。结果提示 :一次性电击可以引起大鼠脑内突触界面结构发生可塑性变化。
The changes of some parameters of GrayⅠ type synaptic interface in the brain of rats treated with one trial electric shock have been quantitatively analyzed with electronic microscopy. The results are as follow:in hippocampal CA 3 area, the postsynaptic density(PSD) was significantly thicker (P<0 05), the width of synaptic cleft was significantly in creased (P<0 01). In the sensorimotor area of cortex, the curvature of synaptic interface was also significantly enlargened (P<0 05). There was no significant difference in the curved type of synaptic interface between the experimental group and control group in above two brains. The results suggest that one trial electric shock can cause synaptic interface structure in the brain of rats to come into being plasticity changes.
出处
《动物学杂志》
CAS
CSCD
北大核心
2000年第1期21-24,共4页
Chinese Journal of Zoology
关键词
突触结构
可塑性
海马CA3区
一次性电击
大鼠
Synaptic plasticity
CA 3 area of hippocampus
Sensorimotor area of cortex
One trial electric shock
Rats