瑞芬太尼复合丙泊酚单肺通气麻醉的临床价值分析

Analysis of clinical value of remifentanil combined with propofol for one-lung ventilation anesthesia

目的探讨瑞芬太尼复合丙泊酚单肺通气麻醉的临床价值。方法 84例患者随机分成两组:实验组42例,瑞芬太尼复合丙泊酚全凭静脉麻醉;对照组42例,瑞芬太尼与异氟烷静吸复合麻醉。观察两组的血流动力学、血气分析及应激激素水平。结果实验组切皮前5min SBP、DBP、HR及术毕前10 minHR明显低于对照组(P<0.05);实验组切皮后30 min SpO2及切皮前5min、切皮后5 min、术毕前10 min PaO2明显高于对照组(P<0.05);实验组切皮后30 min、术毕前10 min Cor、AⅡ及切皮前5 min、切皮后5 min、术毕前10 min的IL-6明显低于对照组(P<0.05)。结论瑞芬太尼复合丙泊酚单肺通气麻醉的效果良好。

Objective To investigate the clinical value of remifentanil combined with propofol for one-lung ventilation anesthesia.Methods 84 patients were randomly and evenly divided into two groups.The treatment group was given remifentanil combined with propofol total intravenous anesthesia,and the control group was given remifentanil and isoflurane inhalation anesthesia.The hemodynamic parameters,arterial blood gas analysis and stress hormones levels were observed and compared between the two groups.Results The levels of SBP,DBP,HR pressure were obviously lower in the treatment group than in the control group 5 minutes before incision（P〈0.05）.The levels of SpO2 30 minutes after incision and PaO2 5 minutes before incision were obviously higher in the treatment group than in the control group（P〈0.05）.The levels of Cor,A Ⅱ and IL-6 were significantly lower in the treatment group than in the control group（P〈0.05）.Conclusion Remifentanil combined with propofol has a favorable anesthesia effect for one-lung ventilation in thoracotomy.