世界食管癌高发区与气候类型

High incidence areas of EC and climate types of the world

目的从宏观五大环境因素之气候方面验证氮循环假说。方法采用世界范围内运用最广之一的柯本气候分组标准,另外用周淑贞改良斯查勒气候分类标准补充;采用世界气象组织与世界卫生组织等公布的各国气候与食管癌资料进行比对。结果现今世界食管癌(特别是鳞癌)高中发地带均位于8个中、低纬度,半干旱、半湿润气候带中:热带干湿气候,热带草原气候,温带草原气候,常湿温暖型气候,冬干湿暖型气候,地中海气候、高原温带半湿润气候,高原温带半干旱气候,与50年前徐致祥教授采用周淑贞改良斯查勒气候分类法,将世界食管癌高发区与其气候一一对比得出的结论相一致。结果从宏观方面进一步支持了氮循环假说。

Nowadays, many scholars believed that the pathogeny of esophageal carcinoma（EC） is greatly attributed to the gene mutation by the interaction of the environment, diet and living habits, etc. While there＇s no consensus on the etiologies of EC, according to ＂the hypothesis of nitrogen cycle-N-nitroso compounds and their precursors of esophageal carcinoma＂, called ＂hypothesis of nitrogen cycle＂for short, raised by XU Zhi-xiang from China, the pathogeny of EC is probably related to the N-nitroso compounds and their precursors which exist extensively in environment come into drinking water. The hypothesis not only expound the epidemiological characteristics of EC with five environmental factors： climate, colliery and farm fertilizer, rivers, degradation time of the precursors, geological and geomorphological factors ; but also has abundant experimental basis and some intervention experiments on the high incidence areas of EC, which have captured a great attention of many scholars.Basing on the interaction of the five environmental factors above, this article list the worldwide climate types and the high incidence areas of EC in detail, and then expatiate the relationship between them. Finally, we find it coincide with the ＂hypothesis of nitrogen cycle＂, which offer a further significant evidence for the hypothesis.