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心血管疾病不容忽视的问题:血管内皮细胞损伤 被引量:22

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摘要 血流剪切力和循环中的激素、酶和小分子物等作为心血管系统功能状态的信息载体通常作用于血管等靶器官维持内环境稳态。内皮细胞是血管壁的重要组成部分。因此,许多常见心血管疾病发病与原发或继发内皮细胞损伤有关。氧化应激反应是心血管疾病导致内皮细胞损伤主要机制,内皮细胞功能障碍后分泌血管活性物质变化,参与心血管疾病发病和进展过程;心血管疾病发病后进一步损伤内皮细胞造成恶性循环。深入认识内皮细胞与心血管疾病的关系具有重大意义。
出处 《转化医学杂志》 2013年第3期173-177,共5页 Translational Medicine Journal
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