摘要
细胞凋亡与程序性死亡是多细胞动物生命过程中必不可少的正常过程 ,它与细胞增殖具有同样重要意义。细胞凋亡与程序性死亡失控不仅扰乱发育 ,还导致病变。因此 ,这一领域的研究受到生命科学研究者的广泛重视 ,进展很快。本文从凋亡的定义、形态学特点、诱导、生物化学背景、基因调控等 5个方面综合分析了近年来国内外的研究进展。
Apoptosis and programmed cell death are normal processes in multicellular organisms.They are as important as proliferation for tissue development and homeostasis.Disregulation of apoptosis and programmed cell death would not only result in disturbance of tissue development and homeostasis,but would also cause a serial pathological changes.The aim of this review is to summarize the current knowledge on morphology,induction,genetic regulation and biochemical background of apoptosis and programmed cell death.
