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老年轻度认知功能障碍患者事件相关电位P300检测及其意义 被引量：5

Detection and significance of P300 event related potentials in the elderly patients with mild cognitive impairment
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摘要 目的探讨老年轻度认知功能障碍(MCI)患者事件相关电位(ERP)P300的变化及其意义。方法选取认识功能正常的老年人15名为对照组,选取15例MIC患者为研究对象(MIC组),两组均进行听觉P300检测,记录P300波的潜伏期及其波幅。结果 MCI组与对照组比较,P300潜伏期延长,P300波幅降低,差异均有统计学意义(P<0.05)。结论 P300可作为评估认知功能变化和MCI早期诊断的客观电生理指标。 Objective To investigate the elderly of mild cognitive impairment （ MCI ） patients with event related potential （ ERP ） changes and significance of P300. Methods The subjects were divided into control group and MIC group with 15 in each groups. The tow groups were auditory P300 detection, latency and amplitude of P300 wave re- cords. Results In the MCI group compared with the control group, the P300 latency while the amplitude of P300 de- creased, and the difference was statistically significant （P〈0. 05）. Conclusion P300 can objectively electrophysiological index in early diagnosis of change as the assessment of cognitive function and MCI.
作者 刘坤梅 佘晓秋 莫燕
机构地区 四川省第四人民医院神经内科
出处 《西部医学》 2013年第6期852-853,共2页 Medical Journal of West China
关键词 轻度认知功能障碍 事件相关电位 早期诊断 Mild cognitive impairment Event related potentials Early diagnosis
分类号 R743 [医药卫生—神经病学与精神病学]
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参考文献7

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共引文献8

同被引文献51

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引证文献5

二级引证文献29

西部医学
2013年 第6期

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