黄体酮联用美洛昔康治疗肾绞痛疗效观察

The curative effect of Progesterone combined with meloxicam in treating renal colic

目的观察黄体酮联合美洛昔康治疗肾绞痛的疗效和安全性。方法选择临床确诊的84例急性肾绞痛患者,随机分为观察组及对照组各42例,观察组予以黄体酮40mg及美洛昔康15mg肌肉注射,对照组予以阿托品0.5mg肌肉注射,比较两组的疗效、复发率及不良反应。结果观察组总有效率90.48%,对照组总有效率73.81%,两组疗效有明显差异(P<0.05),且复发率及不良反应发生率观察组也均明显低于对照组(P<0.05)。结论黄体酮联合美洛昔康治疗肾绞痛疗效确切,且复发率低,不良反应少,值得临床推广应用。

Objective To observe the curative effect and security of progesterone combined with meloxicam on re- nal colic. Methods 84 patients, who were clinically diagnosed as renal colic, were randomly divided into observation group and control group. The patients in observation group received Progesterone 40rag and meloxicam15mg （ira） ,while the patients in control group received atropine 0. 5rag （ira）. The therapeutic effect, replace rate and side effects in both groups were observed. Results The total effective rate in observation group was 90. 48%, which was 73. 81% in control group, there was obvious difference between two groups（P〈0. 05）. And the replace rate and side effects was lower in observation group than in control group（P（0. 05）. Conclusion The efficacy of progesterone combined with meloxicam in the treatment of renal colic is better than atropine, furthermore, with lower replace rate, few side effects, which is worth application extensively in clinic.