摘要
线虫(Caenorhabditis elegans)是重要的模式生物,其基因组序列分析工作于1998年底基本完成,已有19000多个基因被鉴定。本文概述线虫基因组研究中遗传图谱、物理图谱、序列测定和基因识别等方面的研究成果;以及线虫基因组计划将对生命科学研究产生的影响。
Caenorhabditis elegans, a small free-living nematode worm, has been a particularlyuseful model organism for studying the genetics, behavior, and development of metazoan. The97Mb genomic sequence of C. elegans has been finished in 1998, more than 19 000 predicted geneshave been identified. This article reviews the progress in C. elegans genome research so far andthe influence of the project on life science.
出处
《生命科学》
CSCD
2000年第1期21-25,33,共6页
Chinese Bulletin of Life Sciences
关键词
序列测定
遗传图谱
线虫基因组计划
HGP
Caenorhabditis elegans
genome
genetic map
physical map
sequencing