魔芋葡甘露聚糖治疗代谢综合征的临床研究

Clinical Study on Konjac Glucomannan Treating Metabolic Syndrome

目的:观察魔芋葡甘露聚糖(KGM)对代谢综合征患者的体重指数、腰围、血脂、血压、血糖等的影响。方法:86例代谢综合征患者在不改变原有治疗的基础上给予KGM口服,治疗12周后评价对体重指数、腰围、血脂、血压、血糖等的影响。结果:KGM降低体重指数、腰围、血压、总胆固醇、甘油三酯、低密度脂蛋白、空腹血糖、餐后2 h血糖、糖基化血红蛋白(P<0.01);升高高密度脂蛋白(P<0.01)。结论:KGM防治代谢综合征开发前景广阔。

Objective： To investigate the effects of Konjac Glucomannan （KGM） on BMI, waist circumference, blood fat, blood pressure,blood sugar levels and so on in metabolic syndrome. Methods：To evaluate the effects of KGM on BMI, waist circumference, blood fat, blood pressure and blood sugar levels after adding KGM for 12 weeks to 86 cases of metabolic syndrome patients without changing their former medication. Results：KGM reduced BMI,waist circumference, blood pressure, total cholesterol, trigtyceride, low - density 1 ipoprotein cholesterol, fasting plasma glucose, postprandial glucose and glycosylated hemoglobin （ P 〈 0.01 ） ; increased high - density lipoprotein cholesterol （ P 〈 0.01 ）. Conclusion ： Development prospect for KGM to prevent and treat metabolic syndrome is broad.