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多囊卵巢综合征胰岛素抵抗与性激素及血脂代谢的关系 被引量:45

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摘要 目的探讨多囊卵巢综合征(PCOS)患者的胰岛素抵抗、性激素及血脂代谢之间的关系。方法选择PCOS患者60例,根据体质指数(BMI)分为PCOS肥胖组38例与PCOS非肥胖组22例,并选择同期非内分泌因素的不孕女性50例作为对照组,根据BMI分为肥胖对照组18例与非肥胖对照组32例;PCOS患者根据糖负荷试验后分为PCOS胰岛素抵抗组35例与PCOS非胰岛素抵抗组25例,分别比较各组空腹血腹(GLU)、餐后2 h血糖、血脂水平、性激素水平。结果 PCOS肥胖组、PCOS非肥胖组分别与其相对应对照组的TC、TG、HDL、LDL、apoB、LH、T、Fins比较差异有统计学意义(P<0.05,P<0.01);而FSH、E2、GLU、apoA差异无统计学意义(P>0.05)。PCOS胰岛素抵抗组与PCOS胰岛素非抵抗组的BMI、LDL、apoA、T、TG、HDL、apoB差异有统计学意义(P<0.05,P<0.01);FSH、TC差异无统计学意义(P>0.05)。结论 PCOS患者往往存在血脂及性激素水平的异常,与胰岛素抵抗、高胰岛素血症、肥胖具有一定的关系。
出处 《广东医学》 CAS CSCD 北大核心 2013年第10期1571-1573,共3页 Guangdong Medical Journal
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