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microRNAs与心血管疾病 被引量:5

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摘要 微小核糖核酸(microRNAs,miRNAs)是一类内源性非编码单链小分子RNAs,主要在基因转录后水平调控靶基因的表达。研究发现,miRNAs参与调控心血管疾病(CVD)的多种病理、生理过程,包括心肌肥大、心律失常以及血管生成等。循环miRNAs稳定性高,可望作为CVD诊断的新型标志物和治疗靶点。本文就miRNAs与CVD的最新研究进展进行综述。
作者 汪俊军
出处 《临床检验杂志》 CAS CSCD 北大核心 2013年第5期332-335,共4页 Chinese Journal of Clinical Laboratory Science
基金 国家自然科学基金(81271904)
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