再谈他汀类药物与新发糖尿病的关系及防治

Revaluation of the relationship,use of statins for new onset diabetes

他汀类药物是一类强效降低密度脂蛋白胆固醇药物。控制血脂对预防心血管疾病风险极为重要。及早启动他汀类药物治疗,对降低糖尿病心血管风险意义重大。然而,多个随机对照试验荟萃分析后显示他汀类药物可能导致新发糖尿病,相关机制仍不明确。

Statins, as a kind of most potent lipid-lowering medicine, have being an essential drug of CVD prevention strategies. However, many meta-analyses of RCTs showed that statins may induce new onset diabetes, the related mechanisms are still unknown.