肿瘤晚期患者负性情绪对生活质量的影响

EFFECT OF NEGATIVE MOODS ON QUALITY OF LIFE IN ADVANCED CANCER PATIENTS

目的调查接受姑息治疗的肿瘤晚期患者焦虑、抑郁等负性情绪的发生情况,深入了解和分析焦虑、抑郁对其生活质量的影响。方法采用病例回顾与问卷调查相结合的办法,对肿瘤晚期患者85例进行调查,所用量表为医院焦虑抑郁量表、生活质量测定量表简表。结果①回收有效问卷85份,有焦虑症状者51例(60.00%),其中焦虑临界症状者8例(9.41%),处于焦虑状态者43例(50.59%);有抑郁症状者48例(56.47%),其中有抑郁临界症状者22例(25.88%),处于抑郁状态者26例(30.59%);既有焦虑症状又有抑郁症状41例(48.24%)。②肿瘤晚期患者生活质量较差,各领域评分均低于国内常模(P<0.05),多数对自身生活质量及自身健康状况的评价不满意(分别为66.27%、71.76%)。③焦虑、抑郁得分与生活质量总分及生理、心理、社会关系、环境等各领域得分均呈负相关(P<0.05)。结论肿瘤晚期患者中焦虑、抑郁等负性情绪发生率高,影响到生理、心理、社会关系、环境等各领域,需加强重视及积极治疗。

ABSTRACT： Objective To evaluate the anxiety and depression in advanced cancer patients received palliative care and to analyze their relationship with quality of life. Methods Eighty-five advanced cancer patients received palliative Care in our department from August 2011 to August 2012 were surveyed with Hospital Anxiety and Depression Scale and WHO QOL-BREF. Results ①All the cases were effective. The anxiety cases were 51 （60. 00% ）, of which 8 cases（9.41% ） were doubtful, and 43 cases（ 50.59% ） were definite; the depressive cases were 48 （56.47%）, with 22 doubtful cases （25.88%） and 26 definite cases （ 30.59% ）. The total cases with anxiety and depression were 41 （48.24%）. ②The scores of quality of life in advanced cancer patients were lower than those in national norms （ P 〈 0.05 ）. Mo＇st of advanced cancer patients were dissatisfied with their QOL and health （66.27% ,71.76%, respectively）. ③Anxiety and depression were inversely related to total sores and all 4 domains of the WHOQOL-BREF （physical health domain, psychological health domain, social relationships domain and environment domain ） （P 〈 O. 05 ）. Conclusion Most of advanced cancer patients experienced anxiety and depression which associated with poor quality of life in different fields. Measures should be taken to control emotional distress so as to improve advanced cancer patients qualityof life.