摘要
Objective:This study was to compare 5 field conformal technique to the intensity modulated radiotherapy (IMRT) 8 fields technique in boosting locally advanced cancer cervix cases after external beam radiotherapy with respect to target volume coverage and dose to normal tissues. Methods:We conducted a single institutional comparative dosimetric analysis of 10 patients with cancer cervix who was presented to radiotherapy department in National Cancer Institute, Cairo in period between June 2012 to September 2012 and received a CRT boost in the place of planned brachytherapy after large field pelvic radiotherapy (PRT) with concurrent chemotherapy were retrospectively identified. All tumors were situated in the low central pelvis. Two plans were done for every patient; one using the 8 fields IMRT and the second one using 5 fields' 3DCRT the two techniques were then compared using dose volume histogram (DVH) analysis for the PTV, bladder, rectum and both femoral heads. Results:Comparing different DVHs, it was found that the planning target volume (PTV) was adequately covered in both plans while it was demonstrates that the 8 fields IMRT technique carried less doses reaching OARs (rectum, bladder, both femoral heads). Conclusion:From the present study, it is concluded that IMRT technique spared more efficiently OARs than CRT technique but both techniques covered the PTV adequately so whenever possible IMRT technique should be used.
Objective： This study was to compare 5 field conformal technique to the intensity modulated radiotherapy （IMRT） 8 fields technique in boosting locally advanced cancer cervix cases after external beam radiotherapy with respect to target volume coverage and dose to normal tissues. Methods： We conducted a single institutional comparative dosimetric analysis of 10 patients with cancer cervix who was presented to radiotherapy department in National Cancer Institute, Cairo in period between June 2012 to September 2012 and received a CRT boost in the place of planned brachytherapy after large field pelvic radiotherapy （PRT） with concurrent chemotherapy were retrospectively identified. All tumors were situated in the low central pelvis. Two plans were done for every patient; one using the 8 fields IMRT and the second one using 5 fields＇ 3DCRT the two techniques were then compared using dose volume histogram （DVH） analysis for the PTV, bladder, rectum and both femoral heads. Results： Comparing different DVHs, it was found that the planning target volume （PTV） was adequately covered in both plans while it was demonstrates that the 8 fields IMRT technique carried less doses reaching OARs （rectum, bladder, both femoral heads）. Conclusion： From the present study, it is concluded that IMRT technique spared more ef- ficiently OARs than CRT technique but both techniques covered the PTV adequately so whenever possible IMRT technique should be used.
关键词
肿瘤
临床
治疗
化疗
cancer cervix
intensity modulated radiotherapy
conformal radiotherapy
