高血压病左室肥厚患者左心功能的磁共振评估

目的利用磁共振成像技术评估高血压病左室肥厚患者的左心功能。方法回顾性分析太原市中心医院收集到的22例健康志愿者(A组)、35例原发性高血压(EH)不合并左心室肥厚(LVH)者(B组)、16例原发性高血压合并左心室肥厚者(C组)的临床资料。用Siemens公司1.5T超导型磁共振扫描仪(Sonata)分别对三组进行扫描,采用argus软件测量各组左心室功能参数,并对A组左心室功能参数与B、C两组分别进行比较;对B、C两组进行组间比较。结果对照组与B组、C组的射血分数(EF)、左室高峰射血率(PER)、高峰射血时间(TPER)、高峰充盈率(PFR)、高峰充盈时间分别比较,差异均有统计学意义(P<0.05);B组与C组的各项指标比较,差异均有统计学意义(P<0.05)。结论利用磁共振成像技术可以全面评估左心室肥厚患者的心功能;高血压可引起左心室的收缩、舒张功能减低,并且高血压合并左室肥厚可进一步加重收缩、舒张功能的改变。

Objective MRI assess left ventricular function in patients with left ventricular hypertensive of hypertensive. Methods Retrospective analysis of the hospital in Taiyuan city center collected 22 cases of healthy volunteers（A group） , essential hypertension （EH） 35 example is in group B and essential hypertension following left ventricular hypertrophy 16 example is the C group. Application of Siemens company 1.5 T type superconducting MRI scanner （Sonata） respectively to three groups scanned, using Argus software to measure the left ventricular function parameters, and Group A left ventricular function parameters to compare the two groups （B, C）, respectively; groups B, C, between groups comparison. Results A group and B group the ejection fraction （EF）, left ventricular peak ejection rate （PER） the the peak ejection time （TPER）, peak filling rate （PFR）, peak filling time were ~ompated, differences were ~tatistical significance （P〈0.05）; A group with the indicators of group C were compared to a combination of B group C, the indicators comparison, the differences were statistically significant （P〈0.05）. Conclusion MRI（magnetic resonance imaging） technology can be overall assessment of left ventrieular hypertrophy patients with cardiac function; High blood pressure can cause left ventrieular diastolic function of shrinkage reducing, and hypertension with left ventricular hypertrophy can accentuate further contraction diastolic function change.