应用精细肝脏外科理念治疗转移性肝癌

Precise liver surgery in the treatment of metastatic liver cancer

回顾性分析46例转移性肝癌患者的临床资料。根据治疗方法分为传统肝切除组27例和精细肝切除组19例。比较两组术中出血量、输血例数、术后肝功能、并发症发生率、住院时间、住院费用以及术后1年肿瘤复发率和1年生存率。结果显示精细肝切除组与传统肝切除组相比,术中出血量和输血例数、术后并发症发生率、平均住院时间、住院费用及术后1年生存率差异无统计学意义;但术后住院时间短,术后丙氨酸氨基转移酶水平低,术后1年肿瘤复发率低(P<0.05);表明应用精细肝脏外科理念治疗转移性肝癌安全、有效、恢复快。

The clinical data of 46 patents with liver metastases who were admitted to the Anhui Provincial Hospital were retrospectively analyzed. Traditional hepatectomy was performed in 27 patients （routine group） and precise hepatectomy in 19 patients （precise group）. The operative blood loss, blood transfusion rate, incidence of postop- erative complications, length of hospitalization, postoperative hospitalization, medical costs, one-year recurrence and survival rate were compared between the two groups of patients. Compared with the traditional hepatectomy group, the precise hepatectomy group had shorter postoperative hospitalization, lower levels of the postoperative ala- nine transaminase at day 1,3 and 5, lower tumor recurrence rate after one year （P 〈 0. 05）. No significant differ- ence was found in operative blood loss, blood transfusion rate, incidence of postoperative complications, length of hospitalization, medical costs and one-year survival rate between the two groups. Precise liver surgery in the treat- ment of metastatic liver cancer is safer, more effective, and followed by shorter recovery time.