除草剂精克草能对黄鳝的遗传毒性及三种物质的抑制作用

Genetic Toxicity in Cells of Monopterus albus by the Herbicide Jing Ke Cao Neng and Inhibition of Three Substances

研究了除草剂精克草能对黄鳝外周血红细胞微核、核异常的诱发作用 .结果表明 ,处理 7d后 ,不同体积分数的精克草能水溶液对黄鳝的微核细胞率等指标有不同程度的提高 ,而且在一定的体积分数下各指标有高峰期 ,说明该药物对黄鳝有一定的遗传毒性 .同时通过研究发现 ,维生素 C、维生素 B2 、β-胡萝卜素与精草克能共同作用时 ,均能显著降低除草剂精草克能的遗传毒性 ,对鱼类有保护作用 .

Induction of micronuclei and nuclear anomalies in the peripheral blood erythrocytes of Monopterus albus by the herbicide Jing Ke Cao Neng was studied.The results show that the herbicide may increase the rate of micronuclei and nuclear anomalies.At certain concentration,the rates of damage items are significantly different from that of control group. At the same time,inhibition of three substances on micronuclei and anomalies induced by the herbicide in the peripheral blood erythrocytes of Monopterus albus was studied.The results show that vitamin B 2,vitamin C, β carotene can all reduce the rate of genetic damage items mentioned above.It suggests that these substances may protect fish cells from damage of the herbicide.