急诊PCI联合替罗非班治疗ST段抬高心肌梗死的临床观察

Observe Effect of Emergent PCI Combined with Tirofiban Treatment on Patients with ST-segment Elevation Myocardial Infarction

目的观察急诊PCI联合替罗非班治疗ST段抬高心肌梗死患者的疗效。方法选择本院2010年1月至2012年11月收治的56例心肌梗死患者,随机分为治疗组29例和对照组27例。治疗组经PCI术开通梗死相关动脉(IRA)后冠状动脉内注入盐酸替罗非班,而后持续泵入至术后24～48h。对照组应用常规PCI,对两组患者的PCI术后血流效果进行比较。结果治疗组急诊PCI术后TIMI血流3级的发生率(96.5%)较对照组(85.2%)显著增加(P<0.05)。结论替罗非班可改善STEMI患者梗塞相关血管PCI术后的TIMI血流。

Objective To observe effect of emergent PCI combined with tirofiban treatment on patients with ST-segment elevation myocardial infarction. Method Select 56 eases patients with myocardial infarction in our hospital from January 2008 to November 2010, Randomly divided into treatment group 29 cases and control group 27 cases, Treatment group inject tirofiban into the coronary artery after opening of infarct-related artery Via emergent PCI, Then continuous pumping tirofiban postoperative24,-48h, Control group receive application of emergent PCI only, Compare effect of blood flow of two groups of patients after PCI. Results The incidence of TIMI blood flow Level 3 of treatment group （96.5%） increase significantly than control group （85.2%） （P〈0.05） after emergent PCI. Conclusion Tirofiban can improved TIMI blood flow, of patients with ST-segment elevation myocardial infarction after PCI of infarct-related artery.