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乳腺癌中CD_(44)S和CD_(44)V_6基因蛋白表达的实验研究

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摘要 细胞黏附因子为一种细胞表面跨膜糖蛋白分子,分布于诸多细胞表面,包括淋巴细胞、单核细胞、RBC,成纤维细胞、上皮细胞、平滑肌细胞及肿瘤细胞等。CD44参与淋巴细胞的激活,以及细胞间透明质酸的特异性黏附,变异性CD44基因的多样性表达与肿瘤的生长、转移、复发等肿瘤生物学行为相关。我们应用免疫组化方法对乳腺癌中CD44S和CD44V6基因蛋白产物表达与组织学分型、脉管浸润、淋巴转移、预后、复发等相关性进行实验研究。
作者 章革 李涛
出处 《中国医药指南》 2013年第11期73-74,共2页 Guide of China Medicine
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