双歧杆菌三联活菌胶囊对根除幽门螺杆菌所致抗生素相关性腹泻的疗效及护理

Efficacy of Bifidobacterium Triple Viable Capsules on Antibiotic-associated Diarrhea Induced by Eradication of HP and Relevant Nursing

为观察口服双歧杆菌三联活菌胶囊联合针对性的护理措施，对根除幽门螺杆菌引起的抗生素相关性腹泻的临床疗效，将100例进行幽门螺杆菌根除治疗后出现抗生素相关性腹泻的患者随机分为观察组（50例）和对照组（50例）。对照组采用口服双八方面体蒙脱石粉治疗，观察组采用口服双歧杆菌三联活菌胶囊治疗，同时辅以针对性的护理措施。观察两组患者服药后的排便次数、大便性状等指标，比较其疗效差异。结果显示，治疗组总有效率为86．0％，对照组总有效率为64．0％，两组差异具有统计学意义（P〈0．05）。同时，观察组患者治疗后腹痛、腹胀、反酸、嗳气等各项消化道症状评分明显优于对照组（P〈0．05）。结果表明，采用双歧杆菌三联活菌胶囊，同时辅以针对性的护理措施，可显著缓解根除幽门螺杆菌引起的抗生素相关性腹泻。

In order to observe the clinical efficacy of Bifidobacterium triple viable capsules combined with targeted nursing on antibiotic-associated diarrhea inuced by H. pylori eradication therapy, 100 cases with antibiotic-associated diarrhea were randomly divided into observation group and control group, 50 cases for each. Smectite powder was given to control group and triple viable capsules to observation group in con- iunction with targeted nursing interventions. Both groups were compared for the frequency of bowel move- ment and stools property after drug administration, then compare the difference of efficacy. The results showed that the total effective rate was 86.0% and 64.0% respectively in treatment group and control group,which showed significant difference（ P 〈0.05）. After treatment, the scores of abdominal pain, dis- tension,acid regurgitation, belching and other digestive symptoms in observation group were superior to those in the controls（ P d0.05）. It is concluded that Bifidobacterium triple viable capsules combined with targeted nursing interventions shows potent effects on antibiotic-associated diarrhea induced by H. pylori targeted.