消化道恶性肿瘤患者腹腔积液量与血清CA125水平关系探讨

Relationship between Ascites volume and Serum CA125 Levels in Digestive Tract Malignant Tumor Patients

目的探讨消化道恶性肿瘤患者腹腔积液量与血清CA125水平的关系。方法采用化学发光法检测213例消化道恶性肿瘤患者和对照组70例血清CA125水平。结果消化道恶性肿瘤患者腹腔积液组的血清CA125水平明显高于非腹腔积液组(P<0.01);中量腹腔积液患者的血清CA125水平与少量腹腔积液患者比明显升高(P<0.01);大量腹腔积液患者的血清CA125水平显著高于中量腹腔积液患者(P<0.01)。结论消化道恶性肿瘤腹腔积液患者血清CA125水平与腹腔积液量有密切的关系。

Objective To discuss the relationship between ascites volume and serum CA125 levels in digestive tract malignant patients.Methods Chemiluminescence method was used to detect the serum CA125 levels in 213 patients with digestive tract malignant tumors and 70 healthy people.Results The serum CA125 levels in ascites group were significantly higher than that in non-ascites group in the digestive tract malignant tumor patients（P＆lt;0.01）.The serum CA125 levels in group with middle volume of ascites were significantly higher than that in group with small amount of ascites（P＆lt;0.01）.Serum CA125 level in patients with massive ascites also significantly higher than that in patients with middle volume ascites（P＆lt;0.01）.Conclusion There is a close relationship between ascites volume and serum CA125 levels in digestive tract malignant tumor patients.