药物流产失败248例患者的相关因素分析

Analysis on related factors of 248 cases of failed drug abortion

目的分析药物流产失败的原因,以严格掌握其适应证及禁忌证。方法对2 366例在天津市塘沽大华院门诊行药物(米非司酮配合米索前列醇)流产失败患者的孕龄、孕产次数、孕囊直径、孕妇年龄、子宫位置方式等进行回顾性分析。结果停经时间长、孕产次数越多、孕囊直径>2 cm、年龄≥35岁、子宫后倾后屈位者,使用药物流产失败率明显增高(P<0.05)。结论影响药物流产成功的因素有孕龄、孕产次数、孕囊直径、孕妇年龄、子宫位置。

[Objective]To analyze the reasons of failed drug abortion, master its indication and contraindication. [Methods]2 366 patients with failed drug abortion, who received the drug abortion （ mifepristone combined with misoprostol I in Tanggu Dahua Hos- pital of Tianjin, were collected, and a retrospective analysis was conducted to analyze their gestational age, times of pregnancy, di- ameter of the gestational sac, age of pregnant women and uterine position. [ Results] The rate of failed drug abortion in patients with the factors of long time of menopause, more pregnant times, diameter of the gestational sac 〉 2 cm, over 35 years old, uterine retro- version retroflexion increased significantly （P 〈0.05}. [ Conclusion] The factors which affect the success rate of drug abortion in- clude gestational age, times of pregnancy, diameter of the gestational sac, age of pregnant women and uterine position.