药物利用指数提高儿科用药剂量的探索

The exploration to using children defined daily dose to assess the rationality of dose in pediatrics

目的探讨儿童药物利用指数对提高儿科用药剂量合理性的帮助。方法通过回顾性统计我院儿科门诊某种儿童药物处方共322张,对性别、年龄及使用情况进行分析,并使用限定日剂量(DDD)和药物的利用指数(DUI)为指标进行统计分析,观察其合理性。结果我院儿科门诊某种儿童药物使用男女比例为4∶1;4～6岁患儿处方占43.17%;DUI值为0.58。结论我院儿科门诊患儿儿童药物使用基本合理,儿童药物利用指数对儿科用药剂量合理性有一定帮助,值得在临床推广应用。

Objective To investigate the effect to children defined daily dose to assess the rationality of dose in pediatrics.Methods 322 formulas in out-patient clinic（OPD） were counted,with the analysis of gender,age,medication frequency and the use condition.Defined daily dose（DDD）and drug use index（DUI）were designated as indexes for statistics,analysis and evaluation.Results The proportion of male and female children received tablets formulas in our hospital was 4：1.In all the formulas,43.17% was for 4 to 6 year old children;The DUI value was 0.58.Conclusion The use of tablets in our hospital was essentially reasonable.The establishment of a cDUI system is a good try in pediatric dosage evaluation.It is worthy of clinical application.