放射性^(90)锶联合手术治疗瘢痕疙瘩的疗效分析

Radioactive strontium 90 combine operation in the treatment of skin keloid efficacy analysis

目的:探讨放射性90锶敷贴联合手术治疗皮肤瘢痕疙瘩的临床疗效。方法:对321例1086处瘢痕病变分别采用单纯放射性90锶照射治疗(对照组,75例,210处)和放射性90锶联合手术治疗(治疗组,246例,876处),并随访2～4年观察疗效。结果:治疗组246例患者876处病灶,其中治愈708处,治愈率80.82%(708/876),有效率91.67%(803/876)。对照组75例患者210处病灶,其中治愈141处,治愈率67.14%(141/210),有效率82.38%(173/210)。两组治愈率、有效率比较有统计学差异。肩背部复发率20.51%(32/156),其他部位复发率7.60%(8/105),肩背部和其他部位复发率有统计学差异,肩背部复发率最高。结论:放射性90锶联合手术治疗瘢痕疙瘩是一种效果较好的方法,具有应用和推广的价值。

Objective：To investigate the treatment of skin keloid with the radioactive strontium 90 combine operation clinical efficacy together. Methods： 1086 sites of keloids in 336 patients were divided into two groups： control group, treated only with 13 radiation （n= 75, s= 210） ; treatment group, withβ radiation after surgical excision （n=261,s=876） ,they were followed up for two years. Treatment were started in the 24 hours after surgery. Results：treatment group：261 patients with 876 keloid skin lesions,708 were cured,the cure rate was 80.82% （ 708/ 876）, eHiciency was 91.67 % （ 803/876）. control group：75 patients with 210 keloid skin lesions,141 were cured, the cure rate was 67.14% （141/210） ,efficiency was 82. 38% （ 173 /210）. There were significant difference efficiency and cure rate between the two groups . The recurrence rate of shoulder and back was 20.51% （32/156）, The other parts was 7.6% （8/105）. There ware significant different recurrence rate in the shoulder and back between the other parts. The recurrence rate in shoulder and back was the highest. Conclusion： The radioactive strontium 90 combined with operation is an effective method of skin keloids. It has application and popularization.