摘要
目的了解医院大肠埃希菌(ECO)的耐药性及其标本来源,为临床治疗及控制医院感染提供依据。方法对2007年1月至2011年12月临床分离的1125株大肠埃希菌的耐药率及标本来源进行回顾性分析。结果 2007年至2011年近5年间头孢噻肟、头孢曲松、头孢他定、氨曲南的耐药率呈逐年上升;亚胺培南、阿米卡星、哌拉西林他唑巴坦、头孢哌酮舒巴坦一直保持较好的抗菌活性;1125株大肠埃希菌株中,产超广谱β-内酰胺酶(ESBLs)的检出率为25.42%,并有逐年上升的趋势。结论临床应加强合理使用抗菌药物的管理,严防耐药菌株引起医院感染和流行。
Objective To investigate their drug resistance and specimen source, provide evidence for hospital survelliance and the control of hospital infection. Methods To make a retrospective analysis the drug sensitivity of the 1125 ECO s that had been separated between 2011and 2007. Results In nearly five years, the drug resistance rate of Cefotaxime, Ceftriaxone, Ceftazidime and AZT had been risen continuously, imipenem, amy card star, Piperacillin/Tazobactam and Cefoperazone Sulbactam has been maintain good antimicrobial activity; in the tested 1125 ECOs, the case detection rate of ESBLs is 25.42% and there is high trend that this rate will go up year by year. Conclusions We should strengthen clinical rational use of antimicrobial agents and Take strict precautions against the hospital infection and popular caused by drug-resistant strain.
出处
《中国医药指南》
2013年第12期40-41,共2页
Guide of China Medicine
