45例肺结核合并肺部感染的病原学探讨与研究

45 Cases of Pulmonary Tuberculosis Complicated with Pulmonary Infection Etiological Study and Research

目的分析肺结核合并肺部感染的患者的致病病原菌分类并探讨临床抗生素的合理应用。方法抽对我院近期内收治的45例肺结核合并肺部感染患者的痰液标本进行病原菌的培养,并进行病原学分析。结果我院此次共计培养病原菌67株,其中革兰阴性杆菌39株、革兰阳性球菌4株、真菌24株;存在合并基础疾病的患者与未合并基础疾病的患者在感染病原菌数量方面比较差异明显(P<0.05);继发性肺结核患者感染多种病原菌的概率明显高于其他类型患者,差异明显(P<0.05)。结论临床面对肺结核合并肺部感染的患者时应及时进行病原学检测,根据痰真菌检测结果合理用药,才能抑制多种病原菌的反复感染,是患者病情得以控制。

Objective To explore the clinical application of antibiotics pathogens classification of pulmonary tuberculosis patients complicated with pulmonary infection. Methods 45 patients with sputum specimens cultured pumping pulmonary tuberculosis complicated with pulmonary infection in our hospital in recent were pathogenic bacteria, and pathogenic analysis. Results The total training in our hospital from 67 bacterial strains, including 39 strains of gram-negative bacillus, 4 strains of gram positive coccus, 24 strains of fungi; comparison of patients with underlying disease was related to the underlying disease not associated with patients in terms of the number of pathogens significantly difference （P〈0.05）; the probability of various pathogenic bacteria infection pulmonary tuberculosis was higher than that of other kinds of patients, significant difference （P〈0.95）. Conclusion Clinical face in patients with pulmonary tuberculosis complicated with pulmonary infection should be promptly for the aetiology, according to sputum fungal detection results of rational use of drugs, repeated infection can inhibit a variety of pathogenic bacteria, is the patient condition to control.