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肾病综合征C反应蛋白和脂蛋白(a)的变化及其相关性研究

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摘要 目的观察C反应蛋白(CRP)和血清脂蛋白(a)[LP(a)]在肾病综合征(NS)、原发性肾小球肾炎患者中的变化以及它们二者之间的关系。方法收集近3年在我科住院的原发性肾病综合症患者45例(24h尿蛋白〉3.5g)为肾综组,同期住院的原发肾小球肾炎有中等量蛋白尿但未达肾病范畴的患者45例(24h尿蛋白1~3.5g)为中等量蛋白尿组,45例健康者作为对照组,分别测定各组C反应蛋白(CRP)和血清LP(a)的水平。结果 CRP、LP(a)水平肾综组、中等量蛋白尿组显著高于对照组(P〈0.01);肾综组显著高于中等量蛋白尿组(P〈0.01)。结论 CRP、LP(a)水平随着尿蛋白的增加而升高,经直线相关分析显示CRP、LP(a)分别与尿蛋白正相关。
出处 《中国医药指南》 2013年第12期240-241,共2页 Guide of China Medicine
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  • 1万赛英,顾卫,谭锋,王金良,吴海科,黄涛.急性脑梗死病人血浆D-二聚体及CD62p含量的动态变化及其意义[J].中西医结合心脑血管病杂志,2006,4(4):298-299. 被引量:13
  • 2Clarkson P, Celermajer DS, Donald AE,et al. Impaired vascular reactivity in insulin-dependent diabetes mellitus is related to disease duration and low density lipoprotein cholesterol levels[J]. J Am Coll Cardiol, 1996,28(3):573-579.
  • 3Haverkate F, Thompson SG, Pyke SD,et al. Production of C-reactive protein and risk of coronary events in stable and unstable angina[J]. Lancet, 1997,349(9050):462-466.
  • 4Sampietro T,Bigazzi F, Dal-Pino B,et al. Increased plasma C-reactive protein in familial hypoalphalipoproteinemia a proinflammatory condition[J]?Circulation,2002,105(1):11-14.
  • 5Rajamannan NM, Subramaniam M,Springett M,et al. Atorvastatin inhibits hypercholesterolemia-induced cellular proliferation and bone matrix production in the rabbit aortic valve[J]. Circulation,2002,105(22):2660-2665.
  • 6Mendall MA, Patel P,Ballam L,et al.C-reactive protein and its relation to cardiovascular-risk factors: a population based cross sectional study[J]. BMJ, 1996,312(7038):1061-1065.
  • 7Libby P,Ridker PM,Maseri A. Inflammation and atherosclerosis[J]. Circulation,2002,105(9):1135-1143.
  • 8Gambino R. C-reactive protein-undervalued, underutilized[J]. Clin Chem, 1997,43(11):2017-2018.
  • 9Rohde LE, Hennekens CH, Ridker PM. Survey of C-reactive protein and cardiovascular risk factors in apparently healthy men[J].Am J Cardiol,1999,84(9):1018-1022.
  • 10Taylor WR. Hypertensive vascular disease and inflammation: mechanical and humoral mechanisms[J]. Curr Hypertens Rep, 1999, 1 (1): 96-101.

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