脐静脉联合外周中心静脉置管在极低出生体重儿中的应用

Application of umbilical venous catheter combined with peripherally inserted central catheter in very low birth weight infants

目的研究脐静脉联合外周中心静脉置管在极低出生体重儿中的应用。方法回顾性分析新生儿重症监护病房极低出生体重儿脐静脉联合外周中心静脉置管的应用,比较导管组(63例)与非导管组(38例)在院内感染、体重增长情况及住院天数方面的差异。结果导管组院内感染率(17%)与非导管组感染率(24%)差异无统计学意义;导管组体重增长(11.7±2.0 g/kg.d)明显高于非导管组(10.6±2.3 g/kg.d);导管组的住院天数(40±11 d)明显短于非导管组(45±14 d);导管组早产儿相关并发症的发生率与非导管组的差异没有统计学意义。结论脐静脉联合外周中心静脉置管在极低出生体重儿的应用中,早产儿体重的增长显著优于非导管组,住院天数明显缩短,而且院内感染有下降的趋势。

Objective To study the application of umbilical venous catheter （UVC） combined with peripherally inserted central catheter （ PICC ） in very low birth weight infants （ VLBWIs ）. Methods A retrospective analysis was performed on the VLBWIs in the neonatal intensive care unit who received UVC combined with PICC （ catheter group, n = 63 ） or did not receive the catheter treatment （ non-catheter group, n = 38 ） to compare the differences in nosocomial infection, weight gain, and length of hospital stay between the two groups. Results The rate of nosocomial infection was 17% in the catheter group and 24% in the non-catheter group （P 〉 0.05 ）. Compared with the non-catheter group, the catheter group had a significantly higher weight gain （ 11.7 ± 2.0 g/kg·d vs 10.6±2.3 g/kg·d ; P 〈 0.05 ） and a significantly shorter length of hospital stay （40±11 days vs 45±14 days; P 〈0.05）. There was no significant difference in the incidence of complications between the two groups. Conclusions Compared with those not receiving catheter treatment, the VLBWIs receiving UVC combined with PICC have a markedly higher weight gain and a markediy shorter length of hospital stay and show a declining trend in the rate of nosocomial infection.