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骨髓增生异常综合征患者调节性T细胞和Th17细胞水平 被引量：6

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摘要 骨髓增生异常综合征（MDS）是一种起源于造血干／祖细胞的恶性克隆性疾病，呈高度异质性，发病机制包括细胞和分子遗传学异常、造血干细胞分化障碍、骨髓细胞过度凋亡、血管新生障碍及免疫介导的骨髓功能抑制等。Nakamura等研究发现部分MDS患者存在免疫功能的异常，
作者 朱雪梅 刘素芳 刘小柳 肖湘 朱世聪 张广森
机构地区 中南大学湘雅二医院血液科
出处 《中华血液学杂志》 CAS CSCD 北大核心 2013年第6期548-549,共2页 Chinese Journal of Hematology
关键词 骨髓增生异常综合征 细胞水平 调节性T细胞 患者 造血干 祖细胞 恶性克隆性疾病 骨髓功能抑制 遗传学异常
分类号 R5 [医药卫生—内科学]
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参考文献8

  • 1Nakamura Y, Yasuoka H, Tsujimoto M, et al. Importance oflymph vessels in gastric cancer ; a prognostic indicator in generaland a predictor for lymph node metastasis in early stage cancer. JClin Pathol, 2006,59:77-82.
  • 2无,吴德沛,阮长耿.骨髓增生异常综合征诊断与治疗专家共识[J].中华血液学杂志,2012,33(4):347-352. 被引量：75
  • 3Brunning RD, Orizi A, Germing U, et al. Myelodysplastic syn-dromes/neoplasms overview. In : WHO classification of haemato-poietic and lymphoid tissues. IARC. Lyon: France, 2008.
  • 4Wang X, Zheng J, Liu J, et al. Increased population of CD4( + )CD25 ( high),regulatory T cells with their higher apoptotic andproliferating status in peripheral blood of acute myeloid leukemiapatients. Eur J Haematol, 2005,75 : 468 *476.
  • 5Kotsianidis I,Bouchliou I,Nakou E,et al. Kinetics, function andbone marrow trafficking of CD4 + CD25 + FOXP3 + regulatory Tcells in myelodysplastic syndromes (MDS). Leukemia, 2009,23:510-518.
  • 6Fozza C, Longu F, Contini S, et al. Patients with early-stage my-elodysplastic syndromes show increased frequency of CD4 + CD25+ CD127 ( low) regulatory T cells. Acta Haematol, 2012, 128 :178-182.
  • 7Solomou EE, Tsanaktsi A, Fertakis V, et al. Overexpansion ofThl7 and Thl/17 cells in patients with myelodysplastic syndrome.ASH Anuual Meeting and Exposition, 50th ed, San Francisco,2008.
  • 8Bouchliou I, Miltiades P, Nakou E, et al. Thl7 and Foxp3( + ) Tregulatory cell dynamics and distribution in myelodysplastic syn-dromes. Clin Immunol, 2011,139:350-359.

共引文献74

同被引文献59

  • 1申蓉,韩俊庆,孙迎红,张捷,马春燕,徐建.骨髓增生异常综合征患者细胞免疫功能及可溶性肿瘤坏死因子受体的研究[J].临床血液学杂志,2006,19(3):139-141. 被引量：2
  • 2Mao-Ping Chu,Dan Wang,Ying-Ying Zhang. Pachyman treatment improves CD4CD25+ Treg counts and serum in- terleukin 4 and interferon levels in a mouse model of Kawasaki disease[J]. Molecular Medicine Reports,2012,5 (5) : 1237-1240.
  • 3Everts B,Smits HH,Hokke CH. I-Ielminths and dendritic cells: sensing and regulating via pattern recognition re- ceptors, Th2 and Treg responses[J]. European Journal of Im- munology,2010,40(6) :1525-1537.
  • 4Dorota Darmochwal-Kolarz,Magdalena Kludka-Sternik, Jacek Tabarkiewicz,et al. The predominance of Thl7 lym- phocytes and decreased number and function of Treg cells in preeclampsia[J]. Journal of Reproductive Immunology, 2012,93(2) :75-81.
  • 5Erfani N,Mehrabadi SM,Ghayumi MA,et al.Increase of regulatory T cells in metastatic stage and CTLA-4 over expression in lymphocytes of patients with non-small cell lung cancer (NSCLC)[J].Lung Cancer,2012,77(2):306-311.
  • 6Schneider T,Kimpfler S,Warth A,et al.Foxp3 (+) regulatory T cells and natural killer cells distinctly infiltrate primary tumors and draining lymph nodes in pulmonary adenocarcinoma[J].J Thorac Oncol,2011,6(3):432-438.
  • 7Zou W,Restifo NP.T(H)17 cells in tumour immunity and immunotherapy[J].Nat RevImmunol,2010,10(4):248-256.
  • 8Martin-Orozco N,Muranski P,Chung Y,et al.T helper 17 cells promote cytotoxic T cell activation in tumor immunity[J].Immunity,2009,31 (5):787-798.
  • 9Grant WB.Does solar ultraviolet irradiation affect cancer mortality rates in China?[J].Asian Pac J Cancer Prev,2007,8 (2):236-242.
  • 10Mohr SB,Garland CF,Gorham ED,et al.Could ultraviolet B irradiance and vitamin D be associated with lower incidence rates of lung cancer?[J].J Epidemiol Community Health,2008,62 (1):69-74.

引证文献6

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中华血液学杂志
2013年 第6期

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