术中冰冻切片诊断肺部肿物427例分析

Analysis of 427 cases of frozen section diagnosis of lung lesions during operation

目的总结冰冻切片诊断肺部病变的体会。方法回顾性分析427例肺部病变冰冻切片诊断资料。结果利用冰冻切片诊断肺部病变,确诊率为96.7%,未确诊率为0.9%,误诊率为2.3%。误诊10例,误诊率最高的病变为硬化性血管瘤(36.4%)、腺癌(3.9%)和鳞状细胞癌(1.7%)。结论冰冻切片是手术中确定肺部病变性质的有效方法。全面的临床资料、充足的标本和仔细的观察是正确诊断的基础,病理医师要具有丰富的专业知识和实践经验才能保证冰冻切片诊断的准确性。

Objective To summarize experience from frozen section diagnosis of lung lesions. Methods The data of 427 lung lesions frozen section diagnoses were analyzed retrospectively. Results The accurate rate of the frozen section method for lung lesions was 96.7 %, the uncertain rate 0.9% , the inaccurate rate 2.3 %. In the 10 misdiagnosed cases, the lesions with the highest misdiagnosis rate were sclerosing hemangioma （ 36.4% ） , adenoearcinoma （ 3.9% ） and squamous cell carcinoma （ 1.7% ）. Conclusions Frozen section can be an effective method in histologie diagnosis of lung lesions during operation. Comprehensive clinical data, sufficient specimen and careful observation are the basis of correct diagnosis. The rich pathological knowledge and abundant practical experience of pathologists are the key in assuring the accuracy of frozen section diagnosis.