注射用重组人Ⅱ型肿瘤坏死因子受体.抗体融合蛋白治疗类风湿关节炎发生桡神经损伤一例
摘要
患者女,68岁,因多关节肿痛20余年于2012年3月初到我院门诊就诊。病史:20余年前,患者无明显诱因出现双手部分近端指间关节肿痛,未予重视及治疗,后逐渐累及双手各掌指及近端指间关节、双腕关节、双肘关节、双肩关节及双膝关节,伴晨僵,持续时间〉1h,无明显雷诺现象、口干、眼干、脱发、反复口腔溃疡等症状。院外不规则使用泼尼松治疗,病情控制不佳,现仍有多关节肿痛。
出处
《中华风湿病学杂志》
CAS
CSCD
北大核心
2013年第6期431-432,共2页
Chinese Journal of Rheumatology
参考文献7
-
1Kameda T,Dobashi H, Kittaka K,et al. A case of rheumatoidarthritis complicated by demyelination in both cerebral cortex andspinal cord during etanercept therapy. Mod Rheumatol, 2008,18:399-402.
-
2Zhou H. Clinical pharmacokinetics of etanercept: a fully human-ized soluble recombinant tumor necrosis factor receptor fusionprotein. J Clin Pharmaeol, 2005 , 45 : 490-497.
-
3Solomon AJ, Spain RI, Kruer MC, et al. Inflammatory neurolog-ical disease in patients treated with tumor necrosis factor alphainhibitors. Multiple Sclerosis (Houndmills,Basingstoke, Eng-land), 2011,17: 1472-1487.
-
4The Lenercept Multiple Sclerosis Study Group and The Universityof British Columbia MS/MRI Analysis Group. TNF neutralizationin MS: results of a randomized,placebo-controlled multicenterstudy. Neurology, 1999,53: 457-465.
-
5Scheinfeld N. A comprehensive review and evaluation of the sideeffects of the tumor necrosis factor alpha blockers etanercept, in-fliximab and adalimumab. J Dermatol Treatment, 2004, 15: 280-294.
-
6Kerensky TA,Gottlieb AB, Yaniv S,et al. Etanercept: efficacyand safety for approved indications. Exp Opin Drug Safety,2012,11: 121-139.
-
7Taoufik E, Tseveleki V, Chu SY, et al. Transmembrane tumournecrosis factor is neuroprotective and regulates experimentalautoimmune encephalomyelitis via neuronal nuclear factor-KB.Brain J Neurol, 2011,134: 2722-2735.
-
1唐茜,徐建华,蔡静,肖会.以关节炎为首发表现的艾滋病一例[J].中华风湿病学杂志,2010,14(11):791-792.
-
2姜淑华.重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白单独治疗1例强直性脊柱炎3年随诊报告[J].中国社区医师(医学专业),2010,12(19):170-171. 被引量:2
-
3顾镭,张缪佳,吕成银,梅焕平,沈友轩.重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白治疗类风湿关节炎出现巩膜炎一例[J].中华风湿病学杂志,2009,13(10):723-724.
-
4林小军.类风湿性关节炎并发于桥本氏甲状腺炎及乳癌术后1例[J].广州医药,2001,32(6):71-71.
-
5王锋,汪年松.注射用重组人Ⅱ型肿瘤坏死因子受体抗体融合蛋白治疗相关的虹膜炎一例[J].中国医师进修杂志,2009,32(3):76-77.
-
6崔晗,王立,李娅,吴庆军,郭伏平,陈华,郑文洁,张奉春.第345例 关节肿痛—皮疹—发热—头痛[J].中华医学杂志,2015,95(33):2720-2722.
-
7何小鹃,李官成.肿瘤基因工程抗体研究进展[J].国外医学(肿瘤学分册),2002,29(4):245-248. 被引量:3
-
8杨垒,张子阳,蒲涛,裘志成,王虹,曹明燕.重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白治疗类风湿关节炎[J].中国实用医刊,2011,38(13):88-89. 被引量:1
-
9胡清,李雪锋,朱大菊.以关节肿痛为首发表现肺癌一例[J].郧阳医学院学报,2001,20(3):137-137.
-
10王春燕,王轶,王丽萍.重组人Ⅱ型肿瘤坏死因子受体-抗体融合蛋白致狼疮样综合征一例[J].中华风湿病学杂志,2008,12(4):288-288. 被引量:2