期刊文献+

咽喉反流的治疗现状及进展 被引量:6

Current situation and development in treatment of laryngopharyngeal reflux
原文传递
导出
摘要 咽喉反流指胃内容物反流进入咽喉部并引起相应损伤,是胃食管反流的形式之一〔1〕。目前主要的治疗仍然着眼于从病因上减少反流的发生,如质子泵抑制剂(proton-pump inhibitor,PPI)、生活方式改变,以及组胺受体阻滞剂、促动力剂、手术等,但近年来也有新的方法涌现,如嗓音治疗以及针对新靶点的药物等。本文对目前存在的治疗方法及其效果的不同观点进行了尽可能全面的归纳总结, The mainstay of treatment of laryngopharyngeal reflux focuses on a concoction involving protonpump inhibitor and modified beneficial behaviors,sometimes referring to medications like H2-R blocker etc.Therapeutic effect seems to be promising although may at times be challenged by conflict researches.Voice therapy and voice parameters emerge to provide a grand new perspective in treatment and evaluation of this disease.
出处 《临床耳鼻咽喉头颈外科杂志》 CAS 北大核心 2013年第12期676-680,共5页 Journal of Clinical Otorhinolaryngology Head And Neck Surgery
关键词 咽喉反流 质子泵抑制剂 嗓音声学参数 laryngopharyngeal reflux proton-pump inhibitor voice parameters
  • 相关文献

参考文献48

  • 1BARRY D W,VAEZI M F.Laryngopharyngeal re-flux:More questions than answers[J].Cleve Clin J Med,2010,77:327-334.
  • 2FORD C.Treatment of chronic posterior laryngitis with esomeprazole[J].Laryngoscope,2006,116:1717-1718.
  • 3STEWARD D L,WILSON K M,KELLY D H,et al.Proton pump inhibitor therapy for chronic laryn-go-pharyngitis:a randomized placebo-control trial[J].Otolaryngol Head Neck Surg,2004,131:342-350.
  • 4NOORDZIJ J P,KHIDR A,EVANS B A,et al.E-valuation of omeprazole in the treatment of reflux lar-yngitis:aprospective,placebo-controlled,random-ized,double-blind study[J].Laryngoscope,2001,111:2147-2151.
  • 5KOUFMAN J A.Low-acid diet for recalcitrant la-ryngopharyngeal reflux:therapeutic benefits and their implications[J].Ann Otol Rhinol Laryngol,2011,120:281-287.
  • 6PARK W,HICKS D M,KHANDWALA F,et al.Laryngopharyngeal reflux:prospective cohort study evaluating optimal dose of proton-pump inhibitor therapy and pretherapy predictors of response[J].Laryngoscope,2005,115:1230-1238.
  • 7NAIBOGLU B,DURMUS R,TEK A,et al.Do the laryngopharyngeal symptoms and signs ameliorate by empiric treatment in patients with suspected laryngo-pharyngeal reflux[J]?Auris Nasus Larynx,2011,38:622-627.
  • 8LAM P K,NG M L,CHEUNG T K,et al.Rabe-prazole is effective in treating laryngopharyngeal re-flux in a randomized placebo-controlled trial[J].Clin Gastroenterol Hepatol,2010,8:770-776.
  • 9REICHEL O,DRESSEL H,WIEDERANDERS K,et al.Double-blind,placebo-controlled trial with es-omeprazole for symptoms and signs associated with laryngopharyngeal reflux[J].Otolaryngol Head Neck Surg,2008,139:414-420.
  • 10MASAANY M,MARINA M B,SHARIFIA EZAT W P,et al.Empirical treatment with pantoprazole as a diagnostic tool for symptomatic adult laryngopha-ryngeal reflux[J].J Laryngol Otol,2011,125:502-508.

同被引文献41

  • 1汪菁峰,袁耀宗,许斌,孙菁.胃食管反流病食管外症状─咽喉炎的临床研究[J].中华消化杂志,2006,26(1):6-9. 被引量:34
  • 2王晓晔,韩德民,叶京英.咽喉反流[J].国际耳鼻咽喉头颈外科杂志,2006,30(5):281-285. 被引量:46
  • 3A1-Sabbagh G, Wo JM. Supraesophageal manifestationa of gastroesophageal reflux disease [J]. Semin Gastroointest Dis, 1999, 10(3): 113-119.
  • 4Chung JH, Tae K, Lee YS,et al. The significance oflaryngopharyngeal reflux in benign vocal rnucosal lesions [J]. Otolaryngol Head Veck Surg, 2009, 141 (3): 369-373.
  • 5Vishirnura K,Fujita H,Tanaka T, et al. F'haryngolaryn- geal reflux in patients who underwent cervical esophago- gastrostorny following esophagectony [J]. Dis Esophagus, 2010,23(5): 353-360.
  • 6AL-SABBAGH G,WO J M.Supraesophageal manifestations of gastroesophageal reflux disease[J].Semin Gastrointest Dis,1999,10:113-119.
  • 7CHUNG J H,TAE K,LEE Y S,et al.The significance of laryngopharyngeal reflux in benign vocal mucosal lesions[J].Otolaryngol Head Neck Surg,2009,141:369-373.
  • 8VISHIRNURA K,FUJITA H,TANAKA T,et al.F'haryngolaryngeal reflux in patients who underwent cervical esophago-gastrostorny following esophagectony[J].Dis Esophagus,2010,23:353-360.
  • 9黄志刚,韩德民.喉显微外科激光技术治疗喉癌[J].中华耳鼻咽喉头颈外科杂志,2008,43(10):798-800. 被引量:16
  • 10李进让.咽喉反流性疾病的诊断和治疗[J].中华耳鼻咽喉头颈外科杂志,2009,44(2):172-176. 被引量:47

引证文献6

二级引证文献41

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部