肿瘤转移动物模型

Animal models of cancer metastasis

研究肿瘤转移需要建立与临床病理过程相近的肿瘤转移动物模型。目前动物模型主要有基因工程模型和异种移植模型，这对探讨肿瘤转移机制、探索实验治疗手段提供了可能的研究工具。其中，细胞株的筛选、实时检测成像技术等都是非常重要的因素。

Animal models using for research the cancer matestasis should be entirely similar to the clin- ical pathological process in patients. Currently, two kinds of animal models with genetic engineering and human tumor xenografts are available in laboratory, which provide a possible research tool to investigate the mechanism of tumor metastasis and explore the experimental treatment. In these models, the techniques including how to select the cell lines and using real-time imaging detection are very important factors.