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内毒素与急性胰腺炎患者并发急性肾损伤的关系 被引量:11

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摘要 目的:探讨内毒素与重症急性胰腺炎(SAP)患者并发急性肾损伤(AKI)的关系。方法:纳入我院2011年1月至2012年7月SAP并发AKI住院患者52例(病理组)与同期SAP无AKI住院患者52例(对照组),收集研究对象临床资料,计算全身炎症反应综合征(SIRS)评分,并采集血液分析两组生化指标、白细胞计数和降钙素原(PCT)水平。结果:病理组SIRS评分为2.66±0.86,对照组为2.30±1.00,两组均存在全身炎症反应,但差异无统计学意义(P>0.05)。病理组PCT为23.24(9.99,70.44)ng/mL,高于对照组的0.23(0.11,0.61)ng/mL(P<0.05)。病理组尿素、肌酐、血胱抑素C分别为19.75(13.44,25.75)mmol/L、344.0(281.8,450.8)mmol/L、3.09(2.43,4.11)μmol/L,高于对照组4.48(3.45,7.48)mmol/L、49.4(43.8,70.6)mmol/L、0.86(0.69,1.02)μmol/L(P<0.05)。结论:内毒素可能是SAP患者并发AKI的关键原因。
出处 《实用医学杂志》 CAS 北大核心 2013年第12期1955-1957,共3页 The Journal of Practical Medicine
基金 四川省科技支撑项目(编号:2010SZ0252)
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