纤溶酶治疗不稳定型心绞痛150例临床疗效观察

Treating effect of fibrinolysin in 150 patients with unstable angina pectoris

目的观察纤溶酶治疗不稳定型心绞痛的疗效。方法150例不稳定型心绞痛（UA）患者随机分为治疗组和对照组。对照组常规治疗；治疗组在常规治疗基础上，予纤溶酶200U加入生理盐水250ml中静滴，每天1次，连用10d。观察两组治疗前后心绞痛发作次数、心电图缺血性ST—T段改善情况和不良反应。结果两组治疗后心绞痛发作次数均减少，心电图缺血性ST—T段均有改善，但治疗组优于对照组，差异有统计学意义（P〈0．05）。结论纤溶酶治疗不稳定型心绞痛安全、有效。

Objective To investigate the treating effect of fibrinolysin in 150 patients with unstable angi- na pectoris. Methods A total of 150 patients with unstable angina pectoris were divided into treatment group and control group randomly. Patients in the control group were given conventional medication, and patients in the treat- ment group were given 200 U fibrinolysin soluted in 250 ml normal saline （QD） additionally for 10 days. Results Reduced the number of angina in two groups, improve the ischemic ST-T in ECG. Two groups, the difference was statistically significant （P〈0.05）. Conclusion Fibrinolysin has treatment effect in unstable angina pectoris patients.