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HOX基因与白血病关系研究进展 被引量:1

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摘要 同源盒基因(homeobox gene,HOX)广泛存在于线虫、果蝇、老鼠和人类等物种,编码的蛋白质为转录因子,通过与其转录协同因子(如PBX和Meis等)的相互作用来调节转录,进而在造血过程中发挥重要作用。近年大量文献报道,
出处 《中国小儿血液与肿瘤杂志》 CAS 2013年第3期142-144,99,共4页 Journal of China Pediatric Blood and Cancer
基金 四川省卫生厅科研课题(20060040)
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  • 1Liu WJ, Huang MX, Guo QL, et al. Effect human cytwn^alovimsinfection on the expression oi Hoxb2 and Hoxb4 genes in the develop-mental process of cord blood erythroid progenitors. Mol Med Rep,2011,4: 1307-1311.
  • 2Wheadon H, Ramsey JM, Dc4>bin E, et oi. Differmtial Hox expressionin murine embryonic stem cell models of nonnal and malignant hemato-poiesis. Stem Cells Dev, 2011,20: 1465-1476.
  • 3Bach C, Buhl S, Mueller D, et al, Leukemogenic transformation byHOXA cluster genes. Blood, 2010,115:2910-2918.
  • 4Thorsteinsdottir II,Mamo A, Kroon E, et al. Overexpression of themyeloid leukemia-associated Hoxa9 gene in bone marrow cellsinduces stem cell expansion. Blood, 2002 , 99:121-129.
  • 5He M, Chen P,Amovitz S, et al. Two isoforms of HOXA9 functiondifferently but work syna^istically in human MLL-xearranged leukemia.Blood Cells Mol Dis, 2012 , 49:102-106.
  • 6Nagel S,Venturini L, Marquez V E, et al. Polycomb repressor conplex2 regulates HOXA9 and HOXAIO, activating ID2 in NK/T-celllines. Mol Cancer, 2010, 9: 151-162.
  • 7Gwin K, Frank E,Bossou A, et al. Hoxa9 regulates Flt3 in lympho-hematopoietic progenitors. Immunol, 2010, 185:6572-6583.
  • 8Hu Y L, Fong S, Largman Ct et al. HOXA9 regulates miH-155 inhematopoietic cells. Nucleic Acids Res, 2010, 38:5472-5478.
  • 9Shah C A, Wang H, Bei L, et al. HoxAlO regulates transcription ofthe gene encoding transforming growth factor beta2 (TGFbeta2) inmyeloid cells. J Biol Chem, 2011, 286:3161-3176.
  • 10Shah CA, Bei L, Wang H, et al. HoxAlO protein regulates transcriptionof gene encoding fibroblast growth factor 2 (FGF2) in myeloid cells.J Biol Chem, 2012,287 : 18230-18248.

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