溶出度测定在药物制剂研发与质量评价中的应用进展

Application Progress of the Dissolution in Pharmaceutical Preparation Research and Quality Evaluation

介绍了药物溶出度及溶出度试验的概念,并着重阐述了溶出度在新药研发的处方筛选、工艺设计、剂型选择和生物利用度预测以及在药物质量控制和再评价方面的应用。

This paper introduced drug dissolution and dissolution test, and emphatically elaborated the application of dissolution in new drug research, such as the prescription screening, process design, formulation selection, bioavailability prediction, and drug quality control and reassessment.