摘要
目的探讨2型糖尿病合并大血管病变患者的血清瘦素水平及其临床意义。方法采用酶联免疫吸附法测定健康对照组、2型糖尿病合并大血管病变组和2型糖尿病未合并大血管病变组患者的血清瘦素水平。结果 2型糖尿病合并大血管病变组患者的瘦素水平显著高于未合并大血管病变组[(10.12±3.44)μg/L比(7.99±3.18)μg/L,P<0.05]和对照组[(10.12±3.44)μg/L比(6.04±1.86)μg/L,P<0.01]。结论 2型糖尿病合并大血管病变的患者血清瘦素水平明显升高,瘦素与糖尿病大血管病变密切相关。
Objective To study the clinical significance of serum Leptin in type 2 diabetic patients with macroangiopathy. Methods A total of 89 type 2 diabetes were divided into two groups： group DM （without macroangiopathy, n = 43 ） and group DMA （ with macroangiopathy, n = 46 ）. And 40 normal subjects were as control group. Serum Leptin of all subjects was measured by ELISA. Results Serum Leptin was significantly higher in group DMA than in group DM [ （ 10. 12 ±3.44） μg/L vs. （7. 99 ±3. 18）μg/L, P〈0.05] and control group I（10.12 ±3.44） pμg/L vs. （6.04 ± 1.86）μg/L P 〈0.01]. Conclusions Serum Leptin in type 2 diabetic patients with macroangiopathy is significantly increased, and Leptin is closely related with macroangiopathy.
出处
《中国心血管杂志》
2013年第3期191-193,共3页
Chinese Journal of Cardiovascular Medicine
关键词
糖尿病
2型
瘦素
大血管病变
Diabetes mellitus, type 2
Leptin
Macroangiopathy
